Strategy and Science
GLP-1 Market sizing & Valuation
This project provides a strategic analysis of the booming GLP-1 market (Wegovy, Zepbound), going beyond the hype to uncover a critical business challenge.
Key Steps:
AI-Powered Data Screening: Leveraged Perplexity to synthesize vast amounts of clinical trial data, financial reports, and real-world evidence studies -> Defined the TAM/SAM/SOM and analyzed the duopoly battle between Novo Nordisk (First Mover) and Eli Lilly (Best-in-Class) -> Retention Analysis: Identified the critical problem, analyzing churn rates, financial barriers, and the rebound effect. -> Strategic Synthesis presented in a comprehensive Strategic Paper.


Bioinformatics research
Computational Neuroscience


This thesis, "Mixed Selectivity Across Three Parietal Areas (V6A, PE, PEc) in Macaque," investigates the neural basis of visuomotor integration in the Posterior Parietal Cortex.
The research quantified neural firing dynamics during a reaching task by employing Poisson Generalized Linear Models (GLMs) and Principal Component Analysis (PCA). This methodology generated Neural Functional Fingerprints to precisely map single-neuron activity to nine behavioral epochs.
The core finding confirms that mixed selectivity is a universal and robust coding strategy across V6A, PE, and PEc. This demonstrates a highly flexible and efficient, distributed network architecture crucial for complex sensorimotor transformations
This research at the University of Oulu focused on processing and analyzing single-cell RNA-seq (scRNA-seq) data for three cancer types (Breast, Lung, Colon). Utilizing a robust R/Bioconductor pipeline (Seurat), I implemented NicheNet analysis to map key intercellular ligand-receptor communication pathways between tumor and stromal cells.
I also co-developed the MASC scoring algorithm to quantify multi-variable biological interactions. This work delivered quantitative insights into shared molecular pathways across cancers, showcasing advanced proficiency in high-dimensional bioinformatics and complex biological data modeling.
Contacts
Write to me for collaborations or questions.
Telephone
cicomancio99@gmail.com
+39 3663065562
© 2025. All rights reserved.
